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Clomine

Clomine, a tricyclic antidepressant, is the 3-chloro derivative of Imipramine. It was thought that tricyclic antidepressants work exclusively by inhibiting the re-uptake of the neurotransmitters norepinephrine and serotonin by nerve cells.

Other names for this medication:
Clofranil, Clomi, Clomifril, Clomijet, Clomilent, Clomine, Clominex, Clomip, Clomipramine, Clomistar, Clonil, Clopic, Ecmin, Lodep, Obsenil, Ocifiril, Ocifril, Ocnil, Syconil, Ultradep

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Also known as: Clomipramine

Description

Clomine is a tricyclic antidepressant that is used to treat symptoms of obsessive-compulsive disorder (OCD), such as recurrent thoughts or feelings and repetitive actions.

Clomine is for use in adults and children at least 10 years old.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.

Call your doctor if your symptoms do not improve, or if they get worse.

If you need surgery, tell your surgeon you currently use Clomine. You may need to stop for a short time.

Do not stop using Clomine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Clomine dosage information

Overdose

If you overdose Generic Clomine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Clomine overdosage: uneven heart rate, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, increased or decreased urination, swelling, shortness of breath, blue lips or fingernails, feeling light-headed, fainting, seizure.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Clomine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Clomine if you are allergic to it, or if you have:

you have recently had a heart attack; or you are allergic to antidepressants such as amitriptyline, amoxapine, trimipramine, desipramine, doxepin, imipramine, nortriptyline, or protriptyline.

Do not use Clomine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

Tell your doctor if you have ever had:

liver disease; kidney disease; bipolar disorder (manic-depression), schizophrenia or other mental illness; alcoholism; a seizure or a head injury; heart disease; low blood pressure; narrow-angle glaucoma; overactive thyroid or adrenal gland tumor (pheochromocytoma or neuroblastoma); or urination problems.

Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with Clomine and cause a serious condition called serotonin syndrome.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or plan to get pregnant. Taking this medicine during late pregnancy may cause withdrawal symptoms in the newborn.

You should not breastfeed while using Clomine.

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